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EC number: 218-507-2 | CAS number: 2167-23-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Experimental starting date: 8-1-2016 Experimental completion date: 8-1-2016
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 121 (Estimation of the Adsorption Coefficient (Koc) on Soil and on Sewage Sludge using High Performance Liquid Chromatography (HPLC))
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
- Specific details on test material used for the study:
- Batch/Lot no.: 1211442406
Appearance: Colorless clear liquid
Storage: Approx. 5°C
Expiry date: December 1, 2022 - Radiolabelling:
- no
- Test temperature:
- 30°C
- Details on study design: HPLC method:
- Column: Grace Platinum Cyano 5μ, 150x4.6mm
Column temperature: 30°C
Injection volume: 20 μL
Mobile phase: Methanol:HPLC grade water = 25:75 (v/v%)
Flow rate: 0.7 mL/min
Detection: UV, 210 nm
Integration software: Chromeleon version 7.2 - Key result
- Sample No.:
- #1
- Type:
- log Koc
- Value:
- 1.91 dimensionless
- Temp.:
- 20 °C
- Details on results (HPLC method):
- In the test, the average log Koc value for the test substance was calculated with the retention time of two injections, using the calibration plot of log k’ versus log Koc of the selected reference substances. The average measured log Koc value for the test substance, as determined from the test, was calculated to be 1.91. The test substance had a Koc of 81.
- Conclusions:
- The adsorption coefficient (Koc) of the test substance was estimated using the High Performance Liquid Chromatography (HPLC) method. The Koc test was performed in accordance with the OECD guideline
121. The data on Koc can be used to predict the potential of the test substance to partition to soil, sediment or sewage sludge.
The average log Koc value for the test substance calculated from the test was 1.91, which is equal to a Koc of 81. - Executive summary:
The adsorption coefficient (Koc) of the test substance was estimated using the High Performance Liquid Chromatography (HPLC) method. The Koc test was performed in accordance with the OECD guideline
121. The data on Koc can be used to predict the potential of the test substance to partition to soil, sediment or sewage sludge.
The average log Koc value for the test substance calculated from the test was 1.91, which is equal to a Koc of 81.
Reference
The average retention times of the reference substances as well as the test substance, corrected for the dead time, are presented below. This table contains also the theoretical log Koc values of the
reference substances as taken from the OECD guideline 121 and the calculated values for log k’.
Average retention times of the reference substances and test substance
Substance |
log Koctheoretical |
Average retention time (min) |
Average net retention time (min) |
Average log k’ |
log Koccalculated |
Thiourea (dead time) |
|
2.64 |
0 |
|
|
Acetanilide |
1.25 |
3.14 |
0.51 |
-0.72 |
|
Methyl benzoate |
1.80 |
3.61 |
0.98 |
-0.43 |
|
Aniline |
2.07 |
3.39 |
0.76 |
-0.54 |
|
Napthalene |
2.75 |
5.25 |
2.62 |
0.00 |
|
1,2,3-trichlorobenzene |
3.16 |
5.04 |
2.41 |
-0.04 |
|
Phenanthrene |
4.09 |
10.40 |
7.76 |
0.47 |
|
Test substance T14013 |
|
3.51 |
0.88 |
-0.48 |
1.91 |
In the test, the average log Koc value for the test substance was calculated with the retention time of two injections, using the calibration plot of log k’ versus log Koc of the selected reference substances. The average measured log Koc value for the test substance, as determined from the test, was calculated to be 1.91. The test substance had a Koc of 81.
Description of key information
The adsorption coefficient (Koc) of the test substance was estimated using the High Performance Liquid Chromatography (HPLC) method. The Koc test was performed in accordance with the OECD guideline
121. The average log Koc value for the test substance calculated from the test was 1.91, which is equal to a Koc of 81.
Key value for chemical safety assessment
- Koc at 20 °C:
- 81
Additional information
[LogKoc: 1.91]
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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