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Diss Factsheets
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EC number: 635-476-4 | CAS number: 88349-88-6
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
Three studies have been performed with aquatic invertebrates and are presented below:
The first study determined the acute toxicity of CGA 153433 (cloquintocet-acid) to Daphnia magna. The study was carried out according to OECD guideline 202. In this limit study Daphnia magna were exposed to CGA 153433 for 48 hours under semi-static conditions with test medium renewal after 24 hours. Nominal concentrations were 0 (control) and 9.7 mg/L, the corresponding mean measured concentrations were 0 and 9.7 mg/L. As the measured concentrations were within 20% of the nominal concentrations the results of the study are expressed in terms on nominal exposure. The 48 hour EC50 was observed to be >9.7 mg/L, the corresponding no-observed effect concentration was 9.7 mg/L.
The second study determined the acute toxicity of XDE-558 (cloquintocet-acid) to the mysid shrimp Americamysis bahia. The study was carried out according to EPA guideline OPPTS 850.1035. In this limit study Americamysis bahia were exposed to XDE-558 (cloquintocet-acid) for 96 hours under semi-static conditions with test medium renewal after 48 hours. Nominal concentrations were 0 (control) and 120 mg/L, the corresponding mean measured concentrations were 0 and 122 mg/L. As the measured concentrations were within 20% of the nominal concentrations the results of the study are expressed in terms of nominal exposure. The 96 hour LC50 was observed to be >120 mg/L, the corresponding no-observed effect concentration was 120 mg/L.
The third study determined the acute toxicity of XDE-558 (cloquintocet-acid) to the Eastern oyster (Crassostrea virginica). The study was carried out according to EPA guideline OPPTS 850.1025. Crassostrea virginica were exposed to XDE-558 (cloquintocet-acid) for 96 hours under flow-through conditions. Nominal concentrations were 0 (control) 13, 22, 36, 60 and 100 mg/L, corresponding mean measured concentrations were 0, 12.6, 21.3, 35.7, 62.7 and 101 mg/L. As the measured concentrations were within 20% of the nominal concentrations the results of the study are expressed in terms of nominal exposure. The 96 hour LC50 was calculated to be >100 mg/L, the corresponding no-observed effect concentration was 100 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 9.7 mg/L
Marine water invertebrates
Marine water invertebrates
- Effect concentration:
- 100 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.