Registration Dossier
Registration Dossier
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EC number: 223-531-1 | CAS number: 3943-97-3
Endpoint summary
Administrative data
Description of key information
No data regarding acute toxicity (oral, dermal or inhalation route) is available for Methyl p-hydroxycinnamate . A data regarding acute oral toxicity is available for free acid 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)- CAS 501-98-4 (LD 50 oral mouse = 2850 mg/ kg).
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
No data regarding acute toxicity (oral, dermal or inhalation route) is available for Methyl p-hydroxycinnamate . A study regarding acute oral toxicity is available for free acid 2-Propenoic acid, 3-(4-hydroxyphenyl)-, (E)- CAS 501-98-4 (LD 50 oral mouse = 2850 mg/ kg)- ref. Gendai no Rinsho. Vol. 3, Pg. 675, 1969 reported in public database ChemIdplus. This data is not suitable for classification purpose according to the CLP Regulation (EC n. 1272/2008) because the body weight of animals and the details of this study are missing (reliability: R4). However this value is still considered enough to avoid concern so no classification is proposed for acute toxicity of Methyl p-hydroxycinnamate according to the CLP regulation (EC n. 1272/2008).
Methyl p-hydroxycinnamate is a transported isolated intermediate, it is used under strictly controlled conditions so the exposure for worker to the substance is minimized and there is no exposure for general population.
Justification for classification or non-classification
Based on Methyl p-hydroxycinnamate is used as intermediate under strictly controlled conditions and based on no troubling data is available for this substance, no classification is proposed for acute toxicity of Methyl p-hydroxycinnamate according to the CLP regulation (EC n. 1272/2008).
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