Registration Dossier
Registration Dossier
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EC number: 203-405-2 | CAS number: 106-51-4
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- genetic toxicity in vitro
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
Data source
Reference
- Reference Type:
- publication
- Title:
- No information
- Author:
- K. Mortelmans
- Year:
- 1 986
- Bibliographic source:
- Environ Mutagen
Materials and methods
Results and discussion
Applicant's summary and conclusion
- Executive summary:
p-Quinone was tested for mutagenicity in the Salmonella/microsome preincubation assay using the standard protocol approved by the National Toxicology Program. p-Quinone was tested at doses of 0.01, 0.03, 0.10, 0.30, 0.33, 1.0, 3.3, 10, 50, and 66 ug/plate in as many as 5 Salmonella typhimurium strains (TA1535, TA1537, TA97, TA98, and TA100) in the presence and absence of rat or hamster liver S-9. p-Quinone was negative in these tests and the highest ineffective dose tested in any Salmonella typhimurium strain was 66 ug/plate.
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