Registration Dossier
Registration Dossier
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EC number: 221-576-1 | CAS number: 3148-73-0
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
EC50(growth)>100 mg/L, 72h, algae, similar to OECD 201, Hutchings 2004
Key value for chemical safety assessment
Additional information
The acute aquatic toxicity of the test substance to the green alga (Selenastrum capricornutum) was tested in a non-GLP algal microplate study for a period of 72 hours. Ten test vessels were prepared for a control of the testing medium (US EPA medium) containing no test substance and five test vessels were prepared for each of the nominal test concentrations of 0.01, 0.1, 1.0, 3.2, 10, 32 and 100 mg/L. In addition, two blank controls containing no algal inoculum were run for each control and test concentration. The initial cell density in the testing well containing 200 µL test solution and 200 µL of algae in exponential growth phase was 0.25 x 10E04 particles per mL. Testing wells were kept at 24 °C ± 2 °C. No adverse effects on the biomass were observed at the time point of 72 hours of exposure up to the highest nominal test concentration of 100 mg/L and the EC50 value after 72 hours hence is greater than 100 mg/L. No adverse effects were reported up to the nominal test concentration of 100 mg/L and the NOEC value after 72 hours hence is 100 mg/L.
The available data is considered relevant, but not to be reliable or adequate for risk assessment or classification and labelling purposes. This endpoint is not considered complete or conclusive.
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