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EC number: 805-675-2
CAS number: 102340-61-4
The aim of the study was to evaluate teh skin irritation potential of
the test item Tocopheryl Glucoside.
The study was conduced on reconstructed human epidermis (SkinEthic skin
irritation test) according OECD guideline n°439.
Culture cells were exposed to test item at 10% and 100% during 42
minutes and the viability was meseared using MTT coloration test.
In the test conditions used, the test item at 10% and 100%,
corresponding to tocopheryl Glucoside concentration at 4,68 and 46,8%,
was not irritant.
Moistening (first treatment) : 30 minutes in CO2 steriliser
Treatment (liquids) : 30 minutes in CO2 steriliser
Treatment (solids) : 90 minutes in CO2 steriliser
Rinse : 12 minutes
Post-incubation : 120 minutes (liquids) or 18 hours (solids) in CO2
The aim of the study was to evaluate the eye irritation potential of the
test item Tocopheryl Glucoside.
The study was conduced on reconstructed human epithelium cornea.
Culture cells were exposed to test item at 10% and 100% during 30 min or
1h30 (for 10% and 100% test item concentrations respectively) and the
viability was meseared using MTT coloration test.
The tests conducted to evaluate the skin and eye irritation potential of
tocopheryl glucoside were in vitro tests.
The results show that test item at 10% and 100%, corresponding to
tocopheryl glucoside concentrations at 4,68 and 46,8 %, was not irritant
neither for skin, nor for eyes.
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