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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Description of key information

EC50, 96 hours > 89.3mg/L (in terms of specific growth rate, biomass, and yield).

NOEC, 96 hours = 54.5 mg/L.

Key value for chemical safety assessment

EC10 or NOEC for freshwater algae:
54.5 mg/L

Additional information

An algal inhibition study was conducted (Huntingdon Life Sciences, 2013) to determine the effect on aquatic plants following exposure to 2-bromo-3,3,3-trifluoropropene. The study was performed according to EC method C3, OECD method 201, and US EPA Office of Chemical Safety and Pollution Prevention (OCSPP) method 850.4500. The study was conducted in compliance with GLP. The test material is highly volatile and would not be expected to reside in the water phase for long following an environmental release; for this reason the study was performed using sealed vessels to prevent loss of the test material, but with a large headspace (more than 50% of the test media volume) in order to reflect the anticipated real-world situation.

The measured concentrations of 2-bromo-3,3,3-trifluoropropene ranged between 11 and 37% of their nominal values at the start of the test and decreased to range from below the limit of quantitation of the analytical method (0.8 mg/L) to 4% of nominal after 96 hours. Quoted endpoints (EC50, NOEC, etc.) for the study were based on initial measured concentrations of the test material in medium.

After 96 hours of exposure, in terms of initial measured concentration, the EI50 values for average specific growth rate, biomass (in terms of cell density) and yield were >89.3 mg/L. The EI5 values were 58.4, 48.2 and 47.8 mg/L respectively. For all parameters, the “no observed effect concentration” (NOEC) was 54.5 mg/L.