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EC number: 939-237-8
CAS number: -
The key study for oral toxicity reports an LD50 value of >5000mg/kg for MCS#10, (undecanol, linear and branched) (Biolab SGS, 1981; rel 2). The key study for inhalation toxicity was read across from undecan-1-ol (CAS 112-42-5), reporting an LC50 value of >700 mg/m3 air in rat (Younger Labs, 1972; rel 2).The key study for dermal toxicity is also read across from undecan-1-ol, and reports an LD50 value of >5010 - <7940mg/kg in rabbit (Younger Labs, 1977; rel 2).
No information was available for the acute
inhalation and dermal toxicity of MCS#10, undecanol, linear and
monobranched alcohols C6 -C12. The data was therefore read across from
1-decanol (CAS 112 -3 0-1) (Scientific Associates Inc, 1977) and
undecan-1 -ol (CAS 112 -42 -5)(Younger Labs, 1972). These substances are
C10 and C11, and exemplary of the category trend of C6 -C12 alcohols in
which the LC50 is expected to be greater than the substantially
saturated vapour concentration. The recorded concentration in the key
study is reported to be 700mg/m3. The saturated vapour concentration
calculated using the ideal gas equation on the basis of the
physicochemical properties of undecan-1 -ol implies that the highest
theoretically achievable vapour concentration for undecanol is less than
the reported value of 700mg/m3. Therefore the recorded concentration in
the key study represents the highest possible exposure concentration and
can be considered for classification purposes.
The key study for acute dermal toxicity,
similarly, represents the category trend and the LD50 of undecanol,
linear and monobranched C6 -C12 alcohols is expected to be of low
In some cases the CAS and chemical identity
stated refer to SDA nomenclature for this substance. in REACH substance
identification it is necessary to be more specific as to the chain
lengths present. Full details may be found in the CSR
Based on the chosen key information, there is no requirement for
classification or labelling of the MCS #10 alcohol (undecanol, linear
and monobranched), in accordance with current EC regulation 1272/2008. Tests
on similar substances included in this category are also supportive of
these results; which do not warrant classification for any acute
toxicity endpoint under DSD or GHS criteria.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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