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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

With high probability not harmful to aquatic algae. 
No toxic effects occur at the range of the substances solubility.
EL50 (72h) and EL10 (72h) > 100 mg/L (nominal, WAF) for growth rate of Desmodesmus subspicatus (OECD 201)

Key value for chemical safety assessment

Additional information

In a GLP guideline study following OECD 201 green algae (Desmodesmus subspicatus) were exposed for 72 hours to

Hexamethylene diisocyanate, oligomers, blocked with dibutylamine [BASF SE, 2012]. Based on the low water solubility of the test item the aquatic toxicity was determined by a water accommodated fraction (WAF) with a nominal loading rate of 100 mg/L. No algal growth inhibition was observed in the treatment compared to the control. Thus, the 72-h EL50 and EL10 for growth rate inhibition is determined to be > 100 mg/L based on nominal concentrations.