Registration Dossier
Registration Dossier
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EC number: 427-370-1 | CAS number: 164288-56-6
Toxicity to reproduction
Administrative data
- Endpoint:
- screening for reproductive / developmental toxicity
- Type of information:
- experimental study planned (based on read-across)
- Justification for type of information:
- See "Attached justification"
Data source
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 422 (Combined Repeated Dose Toxicity Study with the Reproduction / Developmental Toxicity Screening Test)
Test material
- Reference substance name:
- -
- EC Number:
- 427-370-1
- EC Name:
- -
- Cas Number:
- 164288-56-6
- Molecular formula:
- C21H44N3O3Cl
- IUPAC Name:
- {[(2-hydroxyethyl)carbamoyl]methyl}dimethyl(3-octadecanamidopropyl)azanium chloride
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- Based on this feasibility study including:
- the search for similar chemical structures (analogues);
- the bibliographic research on the selected structures;
- the pre-validation of identified data that could be used on these analogues;
it is concluded that a Weight of Evidence can be prepared to fulfil the data gap concerning the endpoint of reprotoxicity.
This approach can be built on existing data on similar substances representing structural parts and potential metabolites of MONTALINE C40 (analogue approach).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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