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Registration Dossier
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Diss Factsheets
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EC number: 905-459-9 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Adsorption / desorption
Administrative data
Link to relevant study record(s)
- Endpoint:
- adsorption / desorption: screening
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2011
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: The study was conducted using a documented method and in compliance with GLP.
- Qualifier:
- according to guideline
- Guideline:
- EU Method C.19 (Estimation of the Adsorption Coefficient (KOC) on Soil and Sewage Sludge Using High Performance Liquid Chromatography (HPLC))
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- HPLC estimation method
- Media:
- soil/sewage sludge
- Radiolabelling:
- no
- Type:
- log Koc
- Value:
- 3.8
- Temp.:
- 30 °C
- Remarks on result:
- other: Recorded temperature was column temperature.
- Endpoint:
- adsorption / desorption
- Remarks:
- adsorption
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: generally accepted calculation method
- Type of method:
- other: calculation
- Media:
- soil
- Type:
- Koc
- Value:
- 4 036
- Type:
- log Koc
- Value:
- 3.606
- Conclusions:
- The calculated soil sorption coefficient Koc=4036 of m- and p-diisopropylbenzene indicates a strong sorption onto soil organic matter.
- Executive summary:
The soil sorption coefficient Koc of diisopropylbenzene was calculated using EPIWIN v3.20, PCKOCWIN v1.66. The calculation yielded a value of 4036 (log Koc=3.606) indicating a strong sorption onto soil organic matter.
- Endpoint:
- adsorption / desorption
- Remarks:
- adsorption
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: peer-reviewed data bank
- GLP compliance:
- not specified
- Type of method:
- other: calculation
- Media:
- soil
- Type:
- Koc
- Value:
- 4 000
- Conclusions:
- The calculation of Koc based on molecular connectivity indexes yielded a value of 4000 and indicates that a strong sorption of diisopropylbenzene onto soil organic matter is to be expected.
- Executive summary:
In the peer-reviewed data bank, a calculated soil sorption coefficient Koc=4000 is reported. The calculation is based on molecular connectivity indexes according to Sabljic A (1987) Environ Sci Technol 21, 358 -366. Based on the estimated Koc, a strong sorption of diisopropylbenzene onto soil organic matter is to be expected.
Referenceopen allclose all
Description of key information
The soil sorption coefficient Koc of p-diisopropylbenzene was estimated by EC HPLC method to be logKoc = 3.8.
Calculation using EPIWIN v3.20, PCKOCWIN v1.66 yielded a value of 4036 (log Koc=3.606).The calculation of Koc based on molecular connectivity indexes yielded a value of 4000 and indicates that a sorption of diisopropylbenzene onto soil organic matter is to be expected.
Key value for chemical safety assessment
- Koc at 20 °C:
- 6 310
Additional information
Reliable data obtained via EC guideline and supported by calculations.
[LogKoc: 3.8]
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