Registration Dossier
Registration Dossier
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EC number: 807-747-9 | CAS number: 144429-84-5
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
The inhibition of the degradation activity of activated sludge is not anticipated when introduced in appropriate low concentrations. No toxic effects occur at the range of solubility.
Key value for chemical safety assessment
Additional information
Assessment of the target substance in a Short term respiration test (OECD 209):
In a short term respiration test according to OECD guideline 209, no respiration inhibition of domestic activated sludge was observed over a period of 3 hours at the highest test substance concentration of 1000 mg/L (2018).
Supporting assessment of a similar substance (EC 406 -040 -9)
In a short term respiration test according to OECD guideline 209, no respiration inhibition of domestic activated sludge was observed over a period of 3 hours at the highest concentration of 100 mg/L (1989).
Supporting assessment of the major degradation product Metilox acid (CAS: 20170-32-5)
In a 3 hours activated sludge respiration inhibition test the IC50 concentration of the test substance was found to be greater than the highest test concentration of 100 mg/L.
In all studies no respiration inhibition could be observed up to the highest test substance concentration.
Based on these results it can be concluded that the inhibition of the degradation activity of activated sludge is not anticipated for the test substance, its major degradation products and impurity Metilox when introduced in appropriate low concentrations.
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