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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
18/12/2012 - 12/3/2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: Study conducted following OECD/EU guideline and in accordance with GLP. Study material is well characterized.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
GLP compliance:
yes (incl. QA statement)
Type of method:
differential scanning calorimetry

Test material

Constituent 1
Chemical structure
Reference substance name:
3,20-bis(ethylenedioxy)pregna-5,7-diene
EC Number:
243-175-0
EC Name:
3,20-bis(ethylenedioxy)pregna-5,7-diene
Cas Number:
19592-55-3
Molecular formula:
C25H36O4
IUPAC Name:
(1S,3aR,9aR,9bS,11aS)-9a,11a-dimethyl-1-(2-methyl-1,3-dioxolan-2-yl)-1,2,3,3a,6,8,9,9a,9b,10,11,11a-dodecahydrospiro[cyclopenta[a]phenanthrene-7,2'-[1,3]dioxolane]
Test material form:
solid: crystalline
Details on test material:
Name of test material (as cited in study report): Proketal; pregna-5,7-diene-3,20-dione, cyclic 3,20-bis(1,2-ethanediyl acetal)
- Substance type: Intermediate
- Physical state: Powder
-

Results and discussion

Boiling point
Atm. press.:
ca. 1 Bar
Decomp. temp.:
> 250 °C
Remarks on result:
other: boiling was not observed below the temperature which reaction and decomposition were observed and therefore the substance has no boiling temperature.

Any other information on results incl. tables

Reaction and/or decomposition of the test substance was observed at temperatures of > 250°C (> 523K). Boiling of the test substance was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test substance has no boiling temperature.

Applicant's summary and conclusion

Conclusions:
Reaction and/or decomposition of the test substance was observed at temperatures of > 250°C (> 523K). Boiling of the test substance was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test substance has no boiling temperature.
Executive summary:

The melting and boiling temperature of the test substance were determined using differential scanning calorimetry (DSC). This technique records the difference in heat flow of two crucibles, one filled with test substance and the other left empty as reference, while these crucibles are subjected to a controlled temperature programme. When the test substance undergoes a transition, such as melting or evaporation, it is indicated by a deviation from the base line of the heat-flow record. Because melting and evaporation are processes in which heat is consumed, for these processes the deviation from the base line is in the endothermic direction. The melting

temperature or boiling temperature (if any) of the test substance is evaluated from the DSC curve as the extrapolated onset temperature of the endothermic melting or evaporation peak.

As a safety precaution for the DSC cell a preliminary test was performed using a thermogravimetricanalyzer (TGA).