Registration Dossier

Administrative data

Description of key information

On the basis of the results obtained and the primary irritation indices calculated it is concluded that the undiluted test substance is a moderate primary skin irritant, both in case of 4 hours contact with the open, non-occluded, rabbit skin and in the case of 4 hours contact with the occluded rabbit skin.

Furthermore, it appeared that the test substance caused more severe irritation of the skin in the closed patch test than in the open test.

Ketimine resin consists of 7.8% butanol (CAS no. 71-36-3), which is classified for Eye Effects Category 1 (H318), as a result Ketimine resin is classified for  Eye Effects Category 1 (H318) as well.

Key value for chemical safety assessment

Skin irritation / corrosion

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irritating)

Eye irritation

Endpoint conclusion
Endpoint conclusion:
adverse effect observed (irreversible damage)

Respiratory irritation

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

Justification for classification or non-classification

On the basis of the results obtained and the primary irritation indices calculated it is concluded that the undiluted test substance is a moderate primary skin irritant, both in case of 4 hours contact with the open, non-occluded, rabbit skin and in the case of 4 hours contact with the occluded rabbit skin.

Ketimine resin consists of 7.8% butanol (CAS no. 71-36-3), which is classified for Eye Effects Category 1 (H318), as a result Ketimine resin is classified for  Eye Effects Category 1 (H318) as well.