Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 480-880-4 | CAS number: 608-23-1
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2003-04-04 to 2003-07-28
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Version / remarks:
- 1993
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- thermal analysis
- Key result
- Melting / freezing pt.:
- -23 °C
- Decomposition:
- no
- Sublimation:
- no
- Remarks on result:
- other: +/- 1 °C
- Conclusions:
- Melting point (OECD 102 - thermal analysis): -23 °C (+/- 1 °C)
- Executive summary:
In a study performed according to OECD 102 compliant with GLP, the melting point (MP) was determined by freezing a 20-mL sample of the test item in a test tube and electronically recording the temperature of the sample as it warmed (in duplicate). The apparatus was calibrated using acetonitrile.
The observed melting point of the test substance 3-chloro-o-xylene, was -23 ± 1 °C.
Reference
'Melting plateaus' were observed for acetonitrile at -44 °C for both duplicate runs, which was slightly lower than the reported MP of -45 °C (Merck, 1976). It was visually observed that approx. half of the CH3CN in the tubes had melted at the plateau temperature of -44 °C. Therefore, melting point results for the Test Substance were corrected for a bias of 1 °C.
`Melting plateaus' were observed for the test item. The inflection points were at approx. -22 °C for both duplicate runs. Therefore, the reported MP of the test item, adjusted for the bias mentioned above, was -23 °C. At this temperature, it was observed that approx. half of the test item in the tubes had melted. Duplicate runs for both the Reference Substance (CH 3CN) and the test item indicated that the experimental error was approx. 1 °C.
Description of key information
Melting point (OECD 102 - thermal analysis): -23 °C (+/- 1 °C)
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- -23 °C
Additional information
In a study performed according to OECD 102 compliant with GLP, the melting point (MP) was determined by freezing a 20-mL sample of the test item in a test tube and electronically recording the temperature of the sample as it warmed (in duplicate). The apparatus was calibrated using acetonitrile.
The observed melting point of the test substance 3-chloro-o-xylene, was -23 ± 1 °C.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
