Registration Dossier
Registration Dossier
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EC number: 265-479-2 | CAS number: 65122-08-9
Endpoint summary
Administrative data
Description of key information
Biodegradation in water:
The biodegradability of the substance was calculated using seven different Biowin 1-7 models of the BIOWIN v4.10 software. The results indicate that test chemical is expected to be not readily biodegradable.
Additional information
Biodegradation in water:
Following different studies includes estimated study for the target chemical and experimental study for read-across analogues which is extracted by using mechanistic approach and functionally and structurally similar to the target chemical to observe the biodegradation rate of test chemical in water.
Estimation Programs Interface Suite was run to predict the biodegradation potential of the test compound in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI LInear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1 -7, respectively) of the BIOWIN v4.10 software. The results indicate that test chemical is expected to be not readily biodegradable.
In second study, aerobic biodegradation experiment was performed for read across chemical using activated sludge at concentration 0.5 g/L dry material as inoculums and initial concentration of chemical taken was 100 mg/L for 42 days. By considering DOC removal parameter read across chemical showed 16 % degradation in 42 days. The read across chemical belongs to D category according to table 1 and 2 as its limit value falls in that range. This percentage value is very less So it is concluded that test chemical is not readily biodegradable.
Last biodegradation study was conducted for 14 days for evaluating the percentage biodegradability of read across chemical. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. After 14 days of incubation Percent biodegradation of read across chemical was observed to be 0% by BOD parameter and 0.7% by HPLC parameter. Thus, based on percentage degradation, read across chemical is considered to be not readily biodegradable in water.
Based on above observations, it is concluded that test chemical is not readily degradable in water.
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