Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
no hazard identified

STP

Hazard assessment conclusion:
no hazard identified

Hazard for air

Hazard for terrestrial organisms

Hazard for predators

Additional information

Data describing the acute aquatic toxicity of iotroxic acid is based on read-across from iotroxic acid, disodium salt. In aqueous solution disodium salt disassociates to iotoxic acid. For details and justification of read-across please refer to the attached report in section 13 of IUCLID.

Two trophic levels (daphnia magna, aquatic algae) are covered by the acute toxicity data set . Chronic data are not available. No adverse effects were observed for both trophic levels:

In an acute immobilization test withDaphnia magna(STRAUS) according to OECD guideline 202, EC guideline Part 2 -Testing Methods, Part C.2 and GLP, the toxic effects of the test item to aquatic invertebrates were determined after 48 h exposure under static conditions. The 48-h EC50was determined to be higher than 1000 mg/L (nominal).

In a 72 hour algal growth inhibition test, cultures ofDesmodesmus subspicatuswere exposed to iotroxic acid, disodium salt under static conditions in accordance with the OECD Guideline 201 (23 March 2006), EC guideline Part 2 - Testing methods, Part C.3 and under GLP. No inhibition of growth (biomass and growth rate) was observed. The ErC50 (growth rate) was > 100 mg/L (nominal).

Conclusion on classification

Based on the results of the acute toxicity tests to aquatic organisms, and taking into account the provisions laid down in Council Directive 67/548/EEC and CLP (GHS), iotroxic acid is not classified with respect to acute and chronic ecotoxicity.