Registration Dossier
Registration Dossier
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EC number: 606-541-4 | CAS number: 2037-95-8
Water solubility
Administrative data
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 018
- Report date:
- 2018
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Type of method:
- column elution method
Test material
- Reference substance name:
- 1,3-benzoxazine-2,4-dione
- Cas Number:
- 2037-95-8
- IUPAC Name:
- 1,3-benzoxazine-2,4-dione
- Test material form:
- solid
Constituent 1
Results and discussion
Water solubility
- Water solubility:
- >= 0.4 - <= 0.45 g/L
- Conc. based on:
- test mat.
- Loading of aqueous phase:
- 5.6 g/L
- Incubation duration:
- >= 0 - <= 3 d
- Temp.:
- 20 °C
- Remarks on result:
- other: pH not reported
- Details on results:
- The concentration of the product in water increased compared to the fresh sample over three days. A contaminant is formed and elutes in the tail of the main product peak. The sample is therefore considered not stable in a solution of water.
Applicant's summary and conclusion
- Conclusions:
- The water solubility of CH02586 was determined to be between 0.40 and 0.45 g/L using the column elution method (OECD 105).
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