Registration Dossier
Registration Dossier
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EC number: 224-756-8 | CAS number: 4477-28-5
Ecotoxicological Summary
Administrative data
Hazard for aquatic organisms
Hazard for air
Hazard for terrestrial organisms
Hazard for predators
Additional information
4-anilinobenzenediazonium hydrogen sulphate was tested for acute aquatic toxicity at two trophic levels (aquatic invertebrates and algae) according to annex VII of the REACH Regulation (EC n.1907/2006).
- EC50 48h Daphnia Magna = 0.36 mg/l (measured initial concentration; 95 % confidence limit: 0.30 – 0.44 mg/l):experimental data obtained testing the substance according to OECD TG 202.
- ErC50 72h Desmodesmus subspicatus = 7.90 mg/l (measured initial concentrations; 95 % confidence limit: 4.19 – 15.16 mg/l): experimental data obtained testing the substance according to OECD TG 201.
Conclusion on classification
According to the CLP Regulation (EC n.1272/2008), the threshold for classification of a substance for acute aquatic toxicity is 1 mg/l. This limit refers to LC50 (96h) for fish, EC50 (48 h) for daphnia and EC50 (72 - 96 h) for algae or aquatic plants.
A study to assess the short-term toxicity to Daphnia Magna of 4-anilinobenzenediazonium hydrogen sulphate was performed and the result of the test was EC50 48h Daphnia Magna = 0.36 mg/l (measured initial concentration; 95% confidence limit: 0.30 – 0.44 mg/l)
Toxicity on algae was assessed in 72 -hour test always on 4-anilinobenzenediazonium hydrogen sulphate and EC50 for algal growth rate was 7.90 mg/l (measured initial concentrations; 95% confidence limit: 4.19 – 15.16 mg/l).
Considering the result of short-term toxicity test to Daphnia Magna (EC50 48h = 0.36 mg/l), 4-anilinobenzenediazonium hydrogen sulphate is classified H400 (acute aquatic toxicity cat.1) according to the CLP Regulation (EC n.1272/2008).
No chronic toxicity data is available from long-term studies. No further investigation is required considering that the substance is present as such in aqueous solution with naturally light exposure less than 30 minutes. Moreover, 4-anilinobenzenediazonium hydrogen sulphate is a monomer, used under strictly controlled conditions to produce the polymer.
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