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EC number: 228-532-0
CAS number: 6290-03-5
The Chemical Safety Assessment according to Annex I indicates that
secondary poisoning is unlikely as substance and its relevant
degradation products decompose rapidly and there is a low potential for
bioaccumulation (Log Kow below 3) (study scientifically not necessary).
The short-term toxicity to terrestrial plants does not need to be
conducted because the substance and its relevant degradation products
decompose rapidly (study scientifically not necessary).
According to ECHA guidance Chapter R.7c: Endpoint specific
guidance, Version 3.0 – June 2017, Section R.7.11.2 the following
applies: QUOTE: “In the case of readily biodegradable substances which
are not directly applied to soil it is generally assumed that the
substance will not enter the terrestrial environment and as such there
is no need for testing of soil organisms is required.” UNQUOTE The
substance (R)-(-)-butane-1,3-diol was shown to be readily biodegradable,
is fully miscible in water and does have a negative log Pow (-0.9).
Finally, no direct application to soil is known and indirect exposure of
soil is also unlikely. The substance is used as intermediate and monomer
in industrial processes, making exposure to soil very unlikely. The
professional and consumer uses in cosmetic, washing and cleaning and
pharmaceutical products do result in aqueous emissions to sewage
treatment plants, in which due to the ready biodegradability the
substance would be entirely biodegraded and thus, exposure to soil
through these uses of the substance is unlikely too. Thus, long-term
exposure to soil is not of concern and no testing for long-term toxicity
to soil organisms is required, based on exposure considerations.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
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