Dysprosium trinitrate

Long-term toxicity to fish

Administrative data

Endpoint:

fish early-life stage toxicity

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Remarks:

original reference not available

Data source

Reference

Reference 1

Reference Type:

other: student thesis

Title:

Aquatisch ecotoxicologisch onderzoek van zeldzame aardmetalen.

Author:

Den Ouden ACPH

Year:

1995

Bibliographic source:

Student Report HLO Delft, under the supervision of Hooftman RN, TNO-MW, Delft

Reference 2

Reference Type:

review article or handbook

Title:

Maximum permissible concentrations and negligible concentrations for Rare Earth elements (REEs)

Author:

Sneller FEC, Kalf DF, Weltje L, Van Wezel AP

Year:

2000

Bibliographic source:

RIVM (Rijksinstituut voor Volksgezondheid en Milieu) Bilthoven, The Netherlands; report 601501 011

Materials and methods

Principles of method if other than guideline:

Not mentioned in Sneller et al. (2000) which guideline was used. Early-life stage toxicity test.

GLP compliance:

not specified

Test material

Test material information

Details on test material:

No details on test material reported in Sneller et al. (2000).

Sampling and analysis

Analytical monitoring:

yes

Details on sampling:

no details on sampling mentioned in Sneller et al. (2000)

Test solutions

Vehicle:

no

Details on test solutions:

no details on test solution preparation mentioned in Sneller et al. (2000)

Test organisms

Test organisms (species):

Danio rerio (previous name: Brachydanio rerio)

Study design

Test type:

semi-static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

30 d

Test conditions

Hardness:

210 mg CaCO3/L

pH:

6.7-8.4

Salinity:

not applicable

Nominal and measured concentrations:

Measured (but not reported)

Details on test conditions:

Test performed in standard test medium (not specified in Sneller et al., 2000).
No further details on test conditions given in Sneller et al. (2000).

Results and discussion

Effect concentrations

Duration:

30 d

Dose descriptor:

NOEC

Effect conc.:

2.6 mg/L

Nominal / measured:

meas. (not specified)

Conc. based on:

element

Basis for effect:

mortality

Remarks on result:

other: unclear whether dissolved or total Dy was measured

Details on results:

30-d NOEC for growth (dry weight) and another unspecified endpoint = 3.0 mg Dy/L
30-d NOEC for fitness (not further specified) = 3.8 mg Dy/L

Applicant's summary and conclusion

Conclusions:

A 30-d early life stage toxicity test with Brachydanio rerio yielded a NOEC of 2.6 mg Dy/L based on fish mortality. Dysprosium concentrations were reported to be measured, however, it is not clear whether total or dissolved dysprosium was measured and what concentrations are used for expressing the effect concentrations.