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EC number: 238-961-5 | CAS number: 14887-42-4
Water solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- water solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From: 14/09/2009 To: 21/09/2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 105 (Water Solubility)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.6 (Water Solubility)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- 22/11/2005
- Type of method:
- flask method
- Water solubility:
- 583 g/L
- Temp.:
- 20 °C
- pH:
- 1
- Details on results:
- The saturation concentration of Potassium pentahydrogen bis(phosphate) was measured using a titration method. The results of the measurements of the test samples are summarised in Table 1. No differenced higher than 8% were found between samples. Therefore, the study is considered to be valid. Corresponding to the analysis he water solubility of the test item was calculated to be 583 g/L.
- Conclusions:
- Interpretation of results: very soluble (> 10000 mg/L)
The water solubility of Potassium pentahydrogen bis(phosphate) was calculated to be 583 g/L (mean value, 17 g/L standard deviation) at 20±1°C. This study is conducted according to an appropriate guideline and under the conditions of GLP and therefore the study is considered to be acceptable and to adequately satisfy both the guideline requirement and the regulatory requirement as a key study for this endpoint.
Reference
Table 1. Results for the determination of the water solubility of the test item.
Age of sample [h] |
Dilution factor |
Titration start volume [mL] |
Volume titrant 1M NaOH [mL] |
Concentration found [mg/L]1 |
Measured pH2after incubation |
24 |
100 |
50 |
2.3693 |
554.6 |
1 |
24 |
100 |
50 |
2.5593 |
599.1 |
1 |
48 |
100 |
50 |
2.4353 |
570.1 |
1 |
48 |
100 |
50 |
2.5154 |
588.8 |
1 |
72 |
100 |
50 |
2.5274 |
591.6 |
1 |
72 |
100 |
50 |
2.5288 |
591.6 |
1 |
|
|||||
Mean value (n=6) |
582.7 |
|
|||
Standard Deviation (n=6) |
16.8 |
|
|||
1 - rounded value calculated from exact raw data
2 - measured with pH indicator strips
Description of key information
One key study exists. The water solubility of potassium pentahydrogen bis(phosphate) was determined according to EU Method A.6 (Water solubility) and under the conditions of GLP.
Key value for chemical safety assessment
- Water solubility:
- 583 g/L
- at the temperature of:
- 20 °C
Additional information
The water solubility of potassium pentahydrogen bis(phosphate) was calculated to be 583 g/L (mean value, 17 g/L standard deviation) at 20±1°C.
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