Registration Dossier
Registration Dossier
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EC number: 200-091-9 | CAS number: 51-35-4
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- calculation (if not (Q)SAR)
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- accepted calculation method
- Principles of method if other than guideline:
- Accepted calculation method
- GLP compliance:
- no
- Analytical monitoring:
- not required
- Test organisms (species):
- other: Fathead minnow
- Test type:
- other: Calculation
- Dose descriptor:
- LC50
- Effect conc.:
- 10 700 mg/L
- Conc. based on:
- test mat.
- Basis for effect:
- mortality (fish)
- Remarks on result:
- other: Calculation
- Validity criteria fulfilled:
- yes
- Conclusions:
- LC50 as predicted by TopKat v6.1: 10700 mg/L.
- Executive summary:
LC50 as predicted by TopKat v6.1: 10700 mg/L
- Endpoint:
- short-term toxicity to fish
- Data waiving:
- study scientifically not necessary / other information available
- Justification for data waiving:
- other:
Referenceopen allclose all
Description of key information
The results from calculations with 3 accepted calculation methods show that the substance has a very low acute aquatic toxicity. Experimnetal data on the acute aquatic toxicity to Daphnia and algae are available. According to OECD 126 threshold concentration will have to be derived from acute algae and daphnia data. Therefore and for the sake of animal welfare an experimental study referring to acute aquatic toxicity to fish is not conducted.
The lowest calculated value is used as LC50.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Dose descriptor:
- LC50
- Effect concentration:
- 10 700 mg/L
Additional information
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
