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EC number: 210-578-8 | CAS number: 619-08-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Endpoint summary
Administrative data
Description of key information
Appearance:
On the basis of physical observation and using the sense of smell, 2-Chloro-4-nitrophenol was determine to be a white powder.
Melting point:
The melting point determination of 2-chloro-4-nitrophenol (CAS No. 619-08-9) was done following OECD Guideline 102 and according to the metal block capillary method. The test was conducted in replicates and mean melting temperature range was determine to be 107.3 - 111°C at 969.2 hPa.
Boiling Point:
The boiling point determination of 2-chloro-4-nitrophenol (CAS No. 619-08-9) was done following OECD Guideline 103 and according to the method of Siwoloboff. The test was conducted in replicates and mean boiling point was determine to be 190.3°C at 968.2 hPa.
Density:
The density of test item 2-chloro-4-nitrophenol (CAS No. 619-08-9)was determined following OECD Guideline 109 and according to the Adapted from ASTM D854-02 using glass pyknometerThe mean density of test item was determine to be 1.5421 g/cm³ at 20 °C and 968.7 hPa..
Particle size distribution:
The particle size distribution of test item 2-chloro-4-nitrophenol (CAS No. 619-08-9 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determine to be in the range of 150 micron to 75 micron.
Vapour pressure:
Vapour pressure of 2-Chloro-4-nitrophenol estimated to be 0.1333 Pa at temperature 25 Deg C.
Partition coefficient:
Based on the available data from handbook, authoritative and modeling databases, the octanol water partition coefficient (log Pow) value of the test substance 2-Chloro-4-nitrophenol was estimated to be 2.55.
Water solubility:
Water solubility of 2-Chloro-4-nitrophenol is determine to be 1490 mg/L at temperature 25 Deg C.
Surface tension:
Based on the data from ACD labs, surface tension for 2-Chloro-4-nitrophenol was predicted to be 0.0622 N/m.
Flash point:
The flash point determination of Test item 2-chloro-4-nitrophenol (CAS No. 619-08-9 )was done. The method is closed cup method using Pensky-Martens Flash Point Apparatus. The mean flash point of the test item was determine to be 128°C at 968.2 hPa.
Auto flammability:
2-Chloro-4-nitrophenol did not catch fire on being exposed to air at room temperature of 27°Cpressure of 966 hPa. This indicates that 2-Chloro-4-nitrophenol is not auto-flammable.
Flammability:
2-Chloro-4-nitrophenol does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-Chloro-4-nitrophenol is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-Chloro-4-nitrophenol was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because the substance contains chemical groups associated with explosive properties which include oxygen, but the calculated oxygen balance is less than - 200.
Oxidizing properties:
The study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied.
Additional information
Appearance:
On the basis of physical observation and using the sense of smell, 2-Chloro-4-nitrophenol was determine to be a white powder.
From other reliable sources it is concluded that chemical 2 -Chloro-4 -nitrophenol is concluded to be white solid needles
Melting point:
The melting point determination of Test item 2-chloro-4-nitrophenol (CAS No. 619-08-9 ) was done as per the test guideline OECD 102. The method followed was according to Capillary/metal block. The mean melting temperature range was determine to be 107.3 -111°C at 969.2 hPa.
From other reliable sources & authorative databases it is concluded that melting point of 2-Chloro-4-nitrophenol is conclude in the range in between 107.5 to 111 Deg C.
Boiling Point:
The boiling point determination of Test item 2-chloro-4-nitrophenol (CAS No. 619-08-9 ) was done as per the test guideline OECD 103. The method followed was according to Siwoloboff. The mean boiling point was determine to be 190.3°C at 968.2 hPa.
Density:
The density of Test item 2-chloro-4-nitrophenol (CAS No. 619-08-9 ) was determined following OECD guideline 109 and according to the methodAdapted from ASTM D854-02.The mean density of the test item was determine to be 1.5421 g/cm³ at 20 °C and 968.7 hPa.
From other reliable sources it is concluded that density of 2 -Chloro-4 -nitrophenol is concluded to be 1.4914 g/cm3 at temperature 25 Deg C & 1.4818 g/cm3 at temperature 25 Deg C.
Particle size distribution:
The particle size distribution of test item 2-chloro-4-nitrophenol (CAS No. 619-08-9 ) was determined by granulometric analysis with rotap sieve shaker. The particle size distribution was determine to be in the range of 150 micron to 75 micron.
Vapour pressure:
Vapour pressure of 2-Chloro-4-nitrophenol estimated to be 0.1333 Pa at temperature 25 Deg C.
Partition coefficient:
Based on the available data in a key study from handbook, authoritative and modeling databases and supporting study from SRC PhysProp authoritative database, the octanol water partition coefficient (log Pow) value of the test substance 2-Chloro-4-nitrophenol was estimated to be 2.55.
In a supportingstudy from modeling database, the partition coefficient (log Pow) value of the test substance 2-Chloro-4-nitrophenol was estimated to be 2.51.
Another supportingstudy from peer reviewed journal indicates that the octanol water partition coefficient of the test substance 2-Chloro-4-nitrophenol was determined to be 2.33.
Thus, based on the available information, the logPow value of the test substance 2-Chloro-4-nitrophenol ranges from 2.33 to2.55, respectively and thus chemical 2-Chloro-4-nitrophenol can be considered to be hydrophilic in nature.
Water solubility:
Water solubility of 2-Chloro-4-nitrophenol is determine to be 1490 mg/L at temperature 25 Deg C.
From above water solubility value it is concluded that 2-Chloro-4-nitrophenol is soluble (1000-10000 mg/L) in water.
Surface tension:
Based on the data from ACD labs, surface tension for 2-Chloro-4-nitrophenol was predicted to be 0.0622 N/m.
Flash point:
The flash point determination of 2-chloro-4-nitrophenol (CAS No. 619-08-9)was done following closed cup method using Pensky-Martens flash point apparatus. The test was conducted in replicates and mean flash point was determine to be 128°C at 968.2hPa.
Auto flammability:
2-Chloro-4-nitrophenol did not catch fire on being exposed to air at room temperature of 27°Cpressure of 966 hPa. This indicates that 2-Chloro-4-nitrophenol is not auto-flammable.
Flammability:
2-Chloro-4-nitrophenol does not indicate any ignition when the flame of bunsen burner having temperature of approximately 950°C is brought in contact with it. Thus it can be concluded that 2-Chloro-4-nitrophenol is not flammable at high temperature. However since such high temperatures are not found under normal circumstances of transportation and use, thus 2-Chloro-4-nitrophenol was considered non-flammable for chemical safety assessment.
Explosiveness:
The study does not need to be conducted because the substance contains chemical groups associated with explosive properties which include oxygen, but the calculated oxygen balance is less than - 200.
Oxidizing properties:
The study does not need to be conducted because the organic substance contains oxygen or halogen atoms which are chemically bonded only to carbon or hydrogen and hence, the classification procedure does not need to be applied.
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