Registration Dossier
Registration Dossier
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EC number: 201-744-0 | CAS number: 87-41-2
Endpoint summary
Administrative data
Description of key information
There is one reliable study available (BASF XXVI/48, 1976) regarding skin and eye irritation. Rabbit skin was exposed to the substance for 1, 5, 15 min and 20 h and observed for 8 days and resulted in erythema and edema scores of 0. The eyes were treated for 1 h and conjunctiva, chemosis and cornea scores could be found that were all fully reversible within the 8 days observation time. Thus, the substance is not irritating to skin and eye.
Key value for chemical safety assessment
Skin irritation / corrosion
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Eye irritation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not irritating)
Additional information
In different tests in rabbit (BASF XXVI/48, 1976) and human (Kaidbey, 1980) the substance was tested for its irritation/corrosion capacity. In skin there were neither edema nor erythema formation or photoallergic reactions to be found. In eye the substance seems to be slightly irritating and corneal opacity can be found that is fully reversibly after 8 days. Therefore the substance can be classified as not irritating.
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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