Registration Dossier
Registration Dossier
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EC number: 249-320-4 | CAS number: 28940-11-6
Melting point / freezing point
Administrative data
Link to relevant study record(s)
- Endpoint:
- melting point/freezing point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- From November 20 to December 07, 2007
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- The study was conducted according to an internationally recognised method, and under GLP. The substance is considered to be adequately characterised with its purity. Therefore full validation applies.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 102 (Melting point / Melting Range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- other: ASTM E537-86
- Principles of method if other than guideline:
- Not applicable
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- UK GLP Compliance Programme (inspected on August 21, 2007/ signed on October 15, 2007)
- Type of method:
- differential scanning calorimetry
- Key result
- Melting / freezing pt.:
- 37.9 °C
- Remarks on result:
- other: accuracy ± 0.5 °C; 311 ± 0.5 K
- Executive summary:
The melting point of the test substance was determined under GLP according to OECD 102 and ASTM E537-86, by differential scanning calorimetry. Two main runs were performed, and the mean final temperature was retained.
The melting temperature of test substance has been determined to be 37.9 ± 0.5 °C (311 ± 0.5 K).
Reference
Table 4.2/1: Melting point – results
Thermal event |
Interpretation |
Temperature (onset) |
|
°C |
K |
||
Thermographic Data - Determination 1 |
|||
Endotherm |
Melting point |
37.93 |
311 |
Thermographic Data - Determination 2 |
|||
Endotherm |
Melting point |
37.80 |
311 |
Mean melting point: 311 ± 0.5 K
Description of key information
Low melting solid.
Key value for chemical safety assessment
- Melting / freezing point at 101 325 Pa:
- 37.9 °C
Additional information
A fully reliable experimental study, conducted according to a recognized OECD method and under GLP, is available. Therefore it is considered as a key study, and the result is retained as key data.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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