Registration Dossier
Registration Dossier
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EC number: 214-426-1 | CAS number: 1126-79-0
PBT assessment
Administrative data
PBT assessment: overall result
- PBT status:
- the substance is not PBT / vPvB
- Justification:
Butyl phenyl ether cannot be classified as “readily biodegradable” according to the OECD Guideline 301D: Closed Bottle Test. Based on this screening level information, butyl phenyl ether is considered Persistent (P). Butylphenol is an impurity. Based on EPISUITE predictions (i.e. BIOWIN v 4.10), butylphenol is predicted to be readily biodegradable, and thus, according to the screening level criteria, butylphenol is not P.
The log Kow of Butyl Phenyl was determined to be 4.26 at 30°C following the OECD Guideline 117:HPLC method.The estimated log Kow of butylphenol was 3.55 according to KOWWIN v 1.68. Neither of these values meet the criteria for Bioaccumulation (B). Thus, based on screening level information, the substance is not B.
The predicted and experimental acute aquatic EC/LC50 values for butyl phenyl ether ranged from 2.1 - 5.77 mg/L across all species and trophic levels. Similarly, based on ECOSAR (v1.11) results using the chemical category of neutral organics, butylphenol (present as an impurity) is predicted to have acute aquatic toxicities in the range of 3.3 – 5.0 mg/L. Neither butyl phenyl ether nor butylphenol are classified as carcinogenic, mutagenic, or reproductively toxic. Likewise, there is no other evidence of chronic toxicity, as identified by the classifications: T, R48, or Xn, R48 according to Directive 67/548/EEC. Based on these toxicity results, neither butyl phenyl ether nor butylphenol is considered to be toxic (T) based on screening level criteria.
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