Registration Dossier
Registration Dossier
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EC number: 214-426-1 | CAS number: 1126-79-0
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- other: QSAR
- Type of information:
- (Q)SAR
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Prediction made with a valid QSAR model; substance was in the applicability domain for the model
- Justification for type of information:
- QSAR prediction: migrated from IUCLID 5.6
Data source
Reference
- Reference Type:
- other: QSAR
- Title:
- Derek Nexus: 4.1.0, Nexus: 2.0.0
- Author:
- The Dow Chemical Company
- Year:
- 2 016
- Bibliographic source:
- QPRF for Skin sensitising prediction
Materials and methods
- Principles of method if other than guideline:
- QSAR prediction made using Derek Nexus: 4.1.0, Nexus: 2.0.0
- Type of study:
- other: QSAR
Test material
- Reference substance name:
- N-butyl phenyl ether
- EC Number:
- 214-426-1
- EC Name:
- N-butyl phenyl ether
- Cas Number:
- 1126-79-0
- Molecular formula:
- C10H14O
- IUPAC Name:
- butoxybenzene
Constituent 1
Results and discussion
Any other information on results incl. tables
The substance was within the applicability domain for the QSAR tool (DEREK). No alerts were identified for skin sensitising potential, thus it was concluded that this substance was unlikely to be a skin sensitiser.
Applicant's summary and conclusion
- Interpretation of results:
- not sensitising
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
- Conclusions:
- The substance was within the applicability domain for the QSAR tool (DEREK). No alerts were identified for skin sensitising potential, thus it was concluded that this substance was unlikely to be a skin sensitiser.
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