Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 246-905-6 | CAS number: 25371-55-5
Water solubility
Administrative data
Link to relevant study record(s)
Description of key information
Under the conditions of this study no definitive experimental determination of the water solubility the test material could be made due to the surface active properties of the test material. Water solubility was determined to be less than 2.2 x10^-4 g/L by HPLC-MS however this is likely to be an over-estimate of the true water solubility of the test material. Estimates of the test materials individual components water solubility were generated using computer software; the water solubility for the three main components ranged from 1.22 x 10^-6 g/L to 2.25 x 10^-6 g/L.
Key value for chemical safety assessment
Additional information
The water solubility of the test material was investigated in accordance with the standardised guidelines OECD 105 under GLP conditions using high performance liquid chromatography (flask method).
The study was awarded a reliability score of 1 in accordance with the criteria set forth by Klimisch et al. (1997).
No definitive experimental determination was possible due to the surface active properties of the test material. Using a flask method based on Method 105 of the OECD Guidelines for the Testing of Chemicals, 27 July 1995, the water solubility was determined visually to be less than 9 x10^-4 g/L of solution at 20.0 ± 0.5 °C. By analysis of the solution resulting from this sample by HPLC-MS, monitoring the major component in the test material, the solubility was determined to be less than or equal to 2.2 x10^-4 g/L of solution at 20.0 ± 0.5 °C. However due to the readiness of the test material to form emulsions in water, the stability of these emulsions to centrifugation and the unsuitability of the filtration techniques for low concentration solutions of hydrophobic substances, it was concluded that the analytical result may continue to overestimate the true water solubility of the test material.
Using predictive fragment constant methodology software, WSKOWWIN, version 1.41, 2000 US Environmental Protection Agency, the water solubility of the individual components in the test material were estimated to be as follows: Dimethyl octadecylphosphonic acid 1.22 x10^-6 g/L, Mono-methyl octadecylphosphonic acid 1.66 x10^-6 and Octadecylphosphonic acid 2.25 x10^-6.
Under the conditions of this study no definitive experimental determination of the water solubility the test material could be made due to the surface active properties of the test material. Water solubility was determined to be less than 2.2 x10^-4 g/L by HPLC-MS however this is likely to be an over-estimate of the true water solubility of the test material.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
