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Physical & Chemical properties

Particle size distribution (Granulometry)

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Reference
Endpoint:
particle size distribution (granulometry)
Type of information:
experimental study
Adequacy of study:
key study
Study period:
16 March 2016
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Qualifier:
according to guideline
Guideline:
ISO 13320 (Particle size analysis - Laser diffraction methods)
Deviations:
no
Qualifier:
according to guideline
Guideline:
other: CIPAC MT 187: Particle Size Analysis by Laser Diffraction
Deviations:
no
GLP compliance:
no
Type of method:
Laser scattering/diffraction
Type of distribution:
mass based distribution
Specific details on test material used for the study:
Identification: FAT 40444/B
Lot: PCR92X140707(China)
Appearance: red powder
Key result
Percentile:
D50
Mean:
6.705 µm
Remarks on result:
other: Result mentioned as L50 (median particle size). Std dev not specified

L10 = 3.831 μm

L90 = 11.468 μm

Conclusions:
Median particle size (L50D) of FAT 40444/B was determined to be 6.705 μm.
Executive summary:

The particle size distribution of FAT 40444/B was determined in a study conducted according to test guidelines CIPAC MT 187 and ISO 13320 -1, using the laser diffraction method with dry dispersion. Master Sizer 2000 from Malvern Instruments with a measuring cell Scirocco was used for this purpose. Based on the findings of the study, the median particle size (L50D) of the test substance was determined to be 6.705 μm.

Description of key information

The particle size distribution of FAT 40444/B was determined in a study conducted according to test guidelines CIPAC MT 187 and ISO 13320 -1, using the laser diffraction method with dry dispersion. Master Sizer 2000 from Malvern Instruments with a measuring cell Scirocco was used for this purpose. Based on the findings of the study, the median particle size (L50D) of the test substance was determined to be 6.705 μm.

Additional information