Registration Dossier
Registration Dossier
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EC number: 405-430-6 | CAS number: 65143-89-7
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
The 21-day No Observed Effect Concentration for reproduction and parental mortality (overall NOEC) was determined to be 1.0 mg/L (nominal) whereas the corresponding measured concentration was 0.70 mg/L.
Key value for chemical safety assessment
Additional information
Dry form of DOWFAX 8390 -D was studied for its ability to influence the reproduction of Daphnia magna according to OECD guideline No. 202. Daphnia were exposed to nominal concentrations of the test material of 0.22, 0.46, 1.0, 2.2, 4.6 and 10.0 mg/l in a semi-static system (renewal of the test medium 3-times per wesk).
Exposure of the Daphnids to 1.0 mg/l DOWFAX 8390-D induced only a slightly lower number of living young as compared to the negative control an effect which was considered to be statistically non-significant. Exposure to higher concentrations (2.2 - 10.0 mg/l) hardly produced any offspring whereas at 0.22 and 0.46 mg/l the reproductive capacity of the Daphnids wss significantiy stimulated. Based on these data the nominal 21 -day No Observed Effect Concentration for reproduction and parental mortality (overall NOEC) was determined to be 1.0 mg/L whereas the corresponding measured concentration was 0.7 mg/L.
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