Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 278-014-3 | CAS number: 74878-48-1
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
The substance can be considered to be not rapidly biodegradable.
Key value for chemical safety assessment
Additional information
Fluorescent Brightener 363 is a cationic benzimidazoles derivative. The substance is not expected to be ready biodegradable because of its chemical structure and its specific function. Commonly, brighteners undergo a primary transformation, i.e. discolourization due to the interrupting the conjugation. Nevertheless, the degradation process involves more steps and take more time.
The biodegradability potential has been investigated by BIOWIN estimation tool, which calculates the probability that a chemical under aerobic conditions with mixed cultures of microorganisms will biodegrade rapidly or slowly. On the basis of the estimation, the substance is expected to be not ready biodegradable.
In addition, multiple studies investigating BOD5 (Biolological Oxygen Demand) and COD (Chemical Oxygen Demand) of the substance are available.
The BOD5/COD ratio was lower than 0.5 in all the available studies; according to the ECHA "Guidance on information requirements and chemical safety assessment - Chapter R.7b: Endpoint specific guidance" (May 2008 version 1.1), if the BOD5:COD ratio is lower than 0.5, it can be expected that the substance is not readily biodegradable.
In conclusion, all the available information agrees to indicate the substance as not rapidly biodegradable.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
