Registration Dossier

Administrative data

Endpoint:
vapour pressure
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2009
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to
Guideline:
OECD Guideline 104 (Vapour Pressure Curve)
Deviations:
no
Qualifier:
according to
Guideline:
EU Method A.4 (Vapour Pressure)
Deviations:
no
GLP compliance:
yes (incl. certificate)
Type of method:
effusion method: by loss of weight or by trapping vaporisate

Test material

Reference
Name:
Unnamed
Type:
Constituent

Results and discussion

Vapour pressureopen allclose all
Temp.:
<= 20 °C
Vapour pressure:
<= 0 Pa
Temp.:
<= 25 °C
Vapour pressure:
<= 0 Pa

Any other information on results incl. tables

The following vapour pressure were determined experimentally and considered as valid (mean and standard deviation given):

 Experiment  T  P  Stand. Dev. P  RSD P
 No.  K  Pa  Pa  %
 1  389.3  3.97 E-03  2.35 E-04  5.9 %
 2  403.5  1.28 E-02  1.28 E-03 10.0 % 

For the test item B 1061, the vapour pressures at 20°C and at 25°C were calculated from the regression equation.

Applicant's summary and conclusion

Executive summary:

The vapour pressure of B 1061 was determined following EU A.4 using the effusion method (weight loss).

Two runs were performed.

In the first run with eleven experiments, vapour pressure was determined at eleven different temperatures. At lower temperatures, no weight loss was detected. At the temperatures 125 and 140 °C (nominal), weight loss was found, but it was suspected that other test items which had shown weight loss at lower temperatures might have influenced the result by contaminating the Knudsen cell. Therefore, it was decided to repeat the experiment.

In the second run with two experiments, vapour pressure was determined at the nominal temperatures 125 °C and 140 °C only. Significant and reproducible weight loss was found. As higher temperatures could not be measured due to the limits of the test system and lower temperatures would not yield significant weight loss, regression was performed over these two temperatures. The values in the table were determined experimentally. Vapour pressures at 20 °C and 25 °C were calculated from the regression equation with:

Vapour pressure at 20 °C:       7.09 E-08 Pa

Vapour pressure at 25 °C:       1.49 E-07 Pa

Both values lie below the threshold of 1 E-05 Pa.