Registration Dossier
Registration Dossier
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EC number: 204-934-1 | CAS number: 129-17-9
Endpoint summary
Administrative data
Link to relevant study record(s)
Description of key information
Low absorption, wide distribution and rapid elimination of the radioactivity of administered (14C) Patent Blue V by the oral route to male Sprague-Dawley rats, indicates that the chemical is most likely to exhibit Low bio-accumulation potential in the organs of living organisms; though there was some evidence for preferential accumulation of radioactivity in the thyroid gland of the rat in the present study.
Key value for chemical safety assessment
- Bioaccumulation potential:
- low bioaccumulation potential
Additional information
In an in-vivo study carried out onSprague-Dawley male rats, upon oral administration, a total of 93 % of the dose appeared in the faeces within 24 hours. Less than 0.5 % of the radioactivity was excreted in the urine (most within the first 4 hours). There was low absorption of the administered chemicals. There was some evidence for preferential accumulation of radioactivity in the thyroid. However, since the majority of the adminstered chemical was eliminated out of the body of the rats, the bio-accumulation potential of the chemicalhydrogen [4-[4-(diethylamino)-2',4'-disulphonatobenzhydrylidene]cyclohexa-2,5-dien-1-ylidene]diethylammonium, sodium salt Synonym: (14C) Patent Blue V appears to be low.
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