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Diss Factsheets

Physical & Chemical properties

Water solubility

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Administrative data

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Reference
Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
test procedure in accordance with generally accepted scientific standards and described in sufficient detail
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
GLP compliance:
no
Type of method:
flask method
Water solubility:
120 460 mg/L
Temp.:
20 °C
pH:
6.28
Details on results:
Reference solutions were measured in the spectrophotometer in quantitative mode, thus generating a calibration curve. Calibration curve was smooth and linear at every concentration. Considering that preliminary test resulted in an absorbance keeping the same shape like the references, its value was considered for the 24 hours' measurement.

Results:

Test 1 (24hs)

123.56

g/l

Test 2 (48hs)

118.02

g/l

Test 3 (96hs)

119.80

g/l

Average solubility

120.46

g/l

Standard deviation

2.83

pH mother solution

5.35

pH saturated solution

6.28
Conclusions:
The water solubility of the tested substance is 120460 mg/l at 20 °C and pH 6.28
Executive summary:

Method:

The substance has been tested for water solubility according to the flask method as reported in the OECD 105 Guideline.

Results:

The water solubility of the substance is 120460 mg/l. The substance is very soluble in water.

Description of key information

120460 mg/l at 20 °C and pH 6.28

Key value for chemical safety assessment

Water solubility:
120 460 mg/L
at the temperature of:
20 °C

Additional information

OECD 105 Guideline.