2-(hydroxymethylamino)ethanol

Vapour pressure

Link to relevant study record(s)

Reference

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Justification for type of information:

data is from safety assessment reports

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7950 (Vapor Pressure)

Principles of method if other than guideline:

The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs.

GLP compliance:

not specified

Type of method:

static method

Specific details on test material used for the study:

Name of test material (as cited in study report): 2-[(Hydroxymethyl)amino] ethanol
Molecular formula: C3H9NO2
Molecular weight: 91.1091 g/mol
Smiles notation: CN(CCO)O
InChI: 1S/C3H9NO2/c14(6)235/h56H,23H2,1H3
Substance Type: Organic
Physical State: Liquid

Key result

Test no.:

#1

Temp.:

25 °C

Vapour pressure:

2 116 Pa

Remarks on result:

other: no other details mentioned

Test no.:

#2

Temp.:

20 °C

Vapour pressure:

1 585 Pa

Remarks on result:

other: no other details mentioned

Conclusions:

The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs
The vapor pressure of 2-[hydroxy(methyl)amino]ethanol at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively.

Executive summary:

The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs

The vapor pressure of the test chemical was determined using the static method presented in the guideline. An instrument constructed by Case Consulting Laboratories, Inc. was used. The zero-indicator and nitrogen pressures were measured using pressure transducers.

The test substance was places in a glass, round-bottomed flask and attached to the instrument. The test substance was degassed by immersing the flask in a dry ice/ethanol bath and applying a high vacuum. The test substance was warmed to room temperature under vacuum, cooled again in dry ice/ethanol and the limited head space was evacuated.

The pressure produced by the test substance at a particular temperature was recorded. The temperature was raised by an arbitrary amount (~9°C), the system brought to thermodynamic equilibrium and the new pressure recorded. This cycle was repeated for a total of four data points. The log of the pressure was plotted against the reciprocal of the absolute temperature. Vapor pressures at 20 and 25°C were calculated from this curve.

No statistics methods were applied.

The vapor pressure of 2-[hydroxy(methyl)amino]ethanol  at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively.

Description of key information

The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLP.

The vapor pressure of 2-[hydroxy(methyl)amino]ethanol  at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively.

Key value for chemical safety assessment

Vapour pressure:

1 585 Pa

at the temperature of:

20 °C

Additional information

The study was conducted according to OPPTS Guidelines 830.7950, and in accordance with GLPs.

The vapor pressure of 2-[hydroxy(methyl)amino]ethanol  at 20.0°C and 25.0°C were 1585 and 2116 Pa respectively.

MPBPVP v1.43 was used to estimate the vapor pressure of 2-[hydroxy(methyl)amino]ethanol. The estimated vapour pressure of 2-[hydroxy(methyl)amino]ethanol at 25 deg C was 3.07 Pa.