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EC number: 207-074-5 | CAS number: 431-47-0
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
Estimation Programs Interface Suite (EPI suite, 2017) was run to predict the biodegradation potential of the test compound Methyl trifluoroacetate (CAS no. 431 -47 -0) in the presence of mixed populations of environmental microorganisms. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical Methyl trifluoroacetate is expected to be not readiliy biodegradable.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Methyl trifluoroacetate(CAS No.431 -47 -0. If released in to the environment, 43.9% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Methyl trifluoroacetate in water is estimated to be 37.5days (900 hrs). The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of Methyl trifluoroacetate in seddiment estimated to be 337.5 days(8100 hrs). however, as the percentage release of test chemical into sediment is less than 1 %(i.e., reported as 0.111%), indicates that Methyl trifluoroacetate is not persistent in sediment.
Biodegradation in soil
The half-life period of Methyl trifluoroacetate (CAS No. 431 -47 -0) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 16.5 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of Methyl trifluoroacetate in soil is estimated to be 75 days (1800 hrs). Based on this half-life value of Methyl trifluoroacetate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low.
Additional information
Biodegradation in water
Predicted data for the target compound methyl 2,2,2-trifluoroacetate (CAS No. 431-47-0) and supporting weight of evidence study for its read across substance were reviewed for the biodegradation end point which are summarized as below:
In a prediction using the Estimation Programs Interface Suite (EPI suite, 2017), the biodegradation potential of the test compoundmethyl 2,2,2-trifluoroacetate(CAS No. 431-47-0) in the presence of mixed populations of environmental microorganisms was estimated.The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical Methyl trifluoroacetate is expected to be not readily biodegradable.
In a supporting weight of evidence study from secondary source (NTRL report, 1993) for the read across chemical Sodium trifluoroacetate (CAS no. 2923-18-4), the experiment was performed to test biodegradability of read across chemical Sodium trifluoroacetate in water for 77 days. The test was conducted in closed BOD bottles using secondary activated sludge at concentration 2 mg dry wt /L as inoculums in dark at temperature 21oC. The initial concentration of test chemical taken was 20mg/L. The sampling was done at every week and oxygen consumption was measured by oxygen meter. With the help of oxygen consumption rate ThOD was calculated using formula. Sodium Acetate was used as reference substance. Overall percent biodegradation of read across chemical Sodium trifluoroacetate observed was 0%. So it is concluded that the chemical Sodium trifluoroacetate is not readily biodegradable.
On the basis of above results for target chemicalmethyl 2,2,2-trifluoroacetate(from EPI suite, 2017) and for its read across substance (from secondary source), it can be concluded that the test substance methyl 2,2,2-trifluoroacetate can be expected to be not readily biodegradable in nature.
Biodegradation in water and sediment
Estimation Programs Interface (EPI Suite, 2017) prediction model was run to predict the half-life in water and sediment for the test compound Methyl trifluoroacetate(CAS No.431 -47 -0. If released in to the environment, 43.9% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of Methyl trifluoroacetate in water is estimated to be 37.5days (900 hrs). The half-life (37.5 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of Methyl trifluoroacetate in seddiment estimated to be 337.5 days(8100 hrs). however, as the percentage release of test chemical into sediment is less than 1 %(i.e., reported as 0.111%), indicates that Methyl trifluoroacetate is not persistent in sediment.
Biodegradation in soil
The half-life period of Methyl trifluoroacetate (CAS No. 431 -47 -0) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (EPI suite, 2017). If released into the environment, 16.5 % of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of Methyl trifluoroacetate in soil is estimated to be 75 days (1800 hrs). Based on this half-life value of Methyl trifluoroacetate, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is low.
On the basis of available information, the test substance methyl 2,2,2-trifluoroacetate can be considered to be not readily biodegradable in nature.
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