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Density

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Reference
Endpoint:
density, other
Remarks:
density
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
guideline study
Justification for type of information:
Experimental test result performed using standard test guidelines
Qualifier:
according to
Guideline:
OECD Guideline 109 (Density of Liquids and Solids)
Principles of method if other than guideline:
The density of Test item 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1 )was determined following OECD guideline 109 and according to the method recommended in the International Pharmacopoeia, fourth Edition, 2014 .
GLP compliance:
no
Type of method:
pour and tap (for solids)
Key result
Type:
pour density
Density:
0.257 g/cm³
Temp.:
24 °C
Remarks on result:
other: No other detail available
Key result
Type:
tap density
Density:
0.334 g/cm³
Remarks on result:
other: at 972.1 hPa.

TEST ITEM DESCRIPTION AND RESULTS :

FOR SOLIDS:

By Pour Density and Tapped Density Method:

    Method Details     Observations

 Remarks if, any

 Guideline

 OECD 109

1st Reading

 2nd Reading

                                        

 Method

 Test methods: Pour density

and tapped density of

powders” recommended in

The International

Pharmacopoeia, Fourth

Edition, 2014

 

 

 Principle of method

 Pour Density: It is the ratio

of known weight of test item

and its volume in graduated

glass cylinder.

Tap Density: It is the

difference between the

volume of test item

measured before & after

tapping in the graduated

glass cylinder.

 

 

 Test temperature (°C)

 

 26.8°C

 28.0°C

 Atmospheric

pressure (in hPa)

 

972.9 hPa 

971.4 hPa

Weight of test

item(m)

 

 10.009

10.015 

 Volume of measuring

cylinder; readability

in g

 

250 ml;2ml 

 250 ml;2ml

 Volume of test item

without tapping (V)

 

 40 ml

 38 ml

 Volume of test item

after tapping ( V1)

After 10 tapping 

 34 ml

 34 ml

   After 50 tapping 30 ml  30 ml
   After 100 tapping  30 ml  30 ml
   After 250 tapping  -  -
   After 500 tapping  -
   After 750 Tapping  -

CALCULATIONS:

FOR SOLIDS:

By Pour Density and Tapped Density Method:

    Parameters Details         Calculated values

Average

Density

    

 1st

Calculation

2nd

Calculation

 Pour Density of test Item

(g/cm³)

= m

V

 

10.009 /40=0.2502


 

10.015/38=0.2635

 0.2568

 Tap density of test Item

(g/cm³)

= m

V1

 

 10.009/30=0.3336

10.015/30 =0.3338 

 0.3337

Conclusions:
The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was determined to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.
Executive summary:

The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was determined to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.

Description of key information

The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was observed to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.

Key value for chemical safety assessment

Additional information

The mean pour density and tapped density of 3-[(4,5-dihydro-3-methyl-5-oxo-1-phenyl-1Hpyrazol-4-yl)azo]-N,N,N-trimethylanilinium chloride (CAS No. 68391-31-1) was observed to be 0.2568 g/cm³ and 0.3337 g/cm³at 27.4 °C and 972.1 hPa.