Registration Dossier
Registration Dossier
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EC number: 203-564-8 | CAS number: 108-24-7
Toxicity to microorganisms
Administrative data
- Endpoint:
- toxicity to microorganisms
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Acceptable publication, which meets standard scientific methods.
Data source
Referenceopen allclose all
- Reference Type:
- publication
- Title:
- Vergleichende Befunde der Schadwirkung gegen Bakterien (Pseudomonas putida) und Blaualgen (Microcistis aeruginosa),
- Author:
- Bringmann G, Kuehn R (1976).
- Year:
- 1 976
- Bibliographic source:
- Gas-Wasserfach, Wasser-Abwasser 117 (9): 410-413
- Reference Type:
- publication
- Title:
- Comparison of the Toxicity Thresholds of Water Pollutants to Bacteria, Algae and Protozoa in Cell Multiplication Inhibition Test
- Author:
- Bringmann G, Kuehn R
- Year:
- 1 980
- Bibliographic source:
- Water Research 14(3): 231-241
- Reference Type:
- publication
- Title:
- Acetic Anhydrid, CAS No. 108-24-7
- Author:
- OECD SIDS
- Year:
- 2 002
- Bibliographic source:
- SIDS Initial Assessment Report for 6th SIAM
Materials and methods
- Principles of method if other than guideline:
- Cell-multiplication inhibition test according to Bringmann.
- GLP compliance:
- no
Test material
- Reference substance name:
- Acetic anhydrid
- IUPAC Name:
- Acetic anhydrid
- Details on test material:
- - Name of test material (as cited in study report): Essigsäureanhydrid
- Analytical purity: not reported
Constituent 1
Sampling and analysis
- Analytical monitoring:
- not specified
Test organisms
- Test organisms (species):
- Pseudomonas putida
Test conditions
- Test temperature:
- 25 °C
- pH:
- 7
- Details on test conditions:
- The inhibition of cell multiplication within the test cultures was measured by an Coulter counter.
Results and discussion
Effect concentrations
- Duration:
- 16 h
- Dose descriptor:
- other: TT
- Effect conc.:
- 1 150 mg/L
- Nominal / measured:
- nominal
- Conc. based on:
- test mat.
- Basis for effect:
- growth inhibition
- Remarks on result:
- other: TT = toxicity threshold
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
