Registration Dossier
Registration Dossier
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EC number: 240-816-6 | CAS number: 16753-62-1
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
A 48-hour EC50 value of >100 mg/l and NOEC of <10 mg/l have been determined for the effects of the read-across substance, dimethoxydimethylsilane (CAS 1112-39-6), on mobility of the freshwater invertebrate Daphnia magna. It is likely that the test organisms were exposed to the hydrolysis products of the read-across substance, i.e. dimethysilanediol and methanol.
Key value for chemical safety assessment
Additional information
No test data for short-term toxicity to aquatic invertebrates are available for dimethoxy(methyl)vinylsilane. However, reliable data have been read-across from the analogue substance dimethoxydimethylsilane (CAS 1112-39-6). The hydrolysis half-life of the registration substance indicates that, under conditions relevant to the short-term invertebrate test, hydrolysis to methylvinylsilanediol and methanol will occur (half-life 18.3 minutes at pH 7, 25°C). The read-across substance, dimethoxydimethylsilane, rapidly hydrolyses to dimethylsilanediol and methanol (half-life <0.6 hours at pH 7, 25°C). The properties of methanol and the justification of read-across are further discussed in the Ecotoxicological information discussion.
A 48-hour EC50 of 169 mg/l has been determined for the effects of trimethoxyvinylsilane on mobility of Daphnia magna.
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