Registration Dossier
Registration Dossier
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EC number: 911-302-5 | CAS number: -
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Two studies were performed to assess the effect of the test item on the respiration of activated sewage sludge. The effect of the test item on the respiration of activated sewage sludge gave a 3-Hour EC50of >1000 mg/l (nominal) in both studies. No effects observed at < 1000 mg/L nominal
All these values are above the measured water solubility. Due to the testing substance is a surfactant, the critical micelle concentration (CMC) was chosen for the determination of the water solubility. CMC which is taken as solubility limit is 26 mg/L at 20°C.
Key value for chemical safety assessment
- EC10 or NOEC for microorganisms:
- 1 000 mg/L
Additional information
Introduction.
Two studies were performed to assess the effect of the test item on the respiration of activated sewage sludge. The method followed was designed to be compatible with the OECD Guidelines for Testing of Chemicals (1984) No 209 "Activated Sludge, Respiration Inhibition Test", Method C.11 of Commission Regulation (EC) No. 440/2008.
Methods.
In both studies activated sewage sludge was exposed to an aqueous dispersion of the test item at concentrations of 100, 180, 320, 580 and 1000 mg/l nominal for a period of 3 hours at a temperature of 21±1°C.
The rate of respiration was determined after 3 hours contact and compared to data for the reference item, Copper(II)sulphate-pentahydrate.
Conclusion.
The effect of the test item on the respiration of activated sewage sludge gave a 3-Hour EC50of >1000 mg/l (nominal) in both studies. In one key study a NOEC of 1000 mg/l nominal was shown.
All these values are above the measured water solubility. Due to the testing substance is a surfactant, the critical micelle concentration (CMC) was chosen for the determination of the water solubility. CMC which is taken as solubility limit is 26 mg/L at 20°C.
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