Registration Dossier
Registration Dossier
Data platform availability banner - registered substances factsheets
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Diss Factsheets
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 227-699-7 | CAS number: 5941-92-4
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Jun - Jul 1996
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: According to OECD guideline under GLP
Cross-referenceopen allclose all
- Reason / purpose for cross-reference:
- reference to same study
- Reason / purpose for cross-reference:
- reference to other study
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 996
- Report date:
- 1996
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 301 B (Ready Biodegradability: CO2 Evolution Test)
- Deviations:
- no
- Principles of method if other than guideline:
- Not relevant
- GLP compliance:
- yes
Test material
- Reference substance name:
- (±)-13-ethyl-3-methoxygona-1,3,5(10),8-tetraen-17-one
- EC Number:
- 227-699-7
- EC Name:
- (±)-13-ethyl-3-methoxygona-1,3,5(10),8-tetraen-17-one
- Cas Number:
- 5941-92-4
- Molecular formula:
- C20H24O2
- IUPAC Name:
- 13-ethyl-3-methoxy-6,7,11,12,13,14,15,16-octahydro-17H-cyclopenta[a]phenanthren-17-one (non-preferred name)
- Details on test material:
- - Name of test material (as cited in study report): Ethyltetraenon
- Analytical purity: 95.9%
- Lot/batch No.: 1114001
Constituent 1
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge, domestic (adaptation not specified)
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 10 mg/L
- Based on:
- DOC
Results and discussion
% Degradation
- Parameter:
- % degradation (CO2 evolution)
- Value:
- 6
- Sampling time:
- 28 d
- Details on results:
- The test compound was degraded to 6% on day 30 (8: 28 days of incubation).
The reference compound sodium acetate was degraded to 70% on day 10 (9 days of incubation) and up to 90% on day 30.
In the toxicity control, the reference compound (sodium acetate) plus the test compound was degraded to 45% on day 30.
Any other information on results incl. tables
Table 1: Biological degradation (cumulative) in percent (corrected for blank C02 production) of ZK 47568
Test | Nominal | Day of sampling | ||||||||
compound | concentration of carbon | 3 | 4 | 7 | 10 | 14 | 18 | 24 | 28 | 30 |
ZK 47568 | 10 mg/I | 1 | 1 | 1 | 1 | 1 | 2 | 3 | 3 | 6 |
Sodium acetate (reference) | 10 mg/I | 14 | 34 | 58 | 70 | 77 | 81 | 85 | 87 | 90 |
ZK 47568 + sodium acetate (toxicity control) | 10 mg/I + | 8 | 19 | 31 | 38 | 41 | 43 | 44 | 45 | 45 |
10 mg/I |
Applicant's summary and conclusion
- Validity criteria fulfilled:
- yes
- Interpretation of results:
- not inherently biodegradable
- Conclusions:
- The test compound ZK 47568 is not readily biodegradable under the conditions of the test and it was not toxic to the microbes of activated sludge.
- Executive summary:
The purpose of this study was to determine the ready biodegradability of Ethylteraenon (ZK 47568). The study was conducted in agreement with the OECD guideline for testing of chemieals, Ready biodegradability: C02-evolution test, no. 301 B.
The test substance ZK 47568 was incubated in an aqueous solution including nutrients with microorganisms from a municipal sewage treatment plant for 28 days (start of treatment = day 1). The nutrient solutions were made up of phosphates, magnesium sulphate, iron chloride, ammonium chloride and calcium chloride. The test substance was incubated in a concentration of 10 mg carbon/L in triplicate. Additionally, a reference substance (sodium acetate) was tested according to the same procedure, in order to verify the viability and activity of the degrading microorganisms. Furthermore, a blank control was tested in triplicate without any test or reference substance. One further set was incubated with sodium acetate as 10 mg carbon/L (reference substance) plus ZK 47568 as 10 mg carbon/L representing a toxicity control. The biological degradation of the test and reference substances was evaluated by measurement of the carbon dioxide (C02) produced during the test period. CO2 production was determined on days 3, 4, 7, 10, 14, 18, 24 and 28. On day 29 the solutions were acidified in order to expel all dissolved CO2 and CO2 was determined on day 30. The CO2 production was calculated as the percentage of total CO2 that the test material could theoretically have produced, based on carbon content. The blank CO2 production was subtracted for correction.
The test compound was degraded to 6% on day 30 (8: 28 days of incubation). The reference compound sodium acetate was degraded to 70% on day 10 (9 days of incubation) and up to 90% on day 30. In the toxicity control, the reference compound (sodium acetate) plus the test compound was degraded to 45% on day 30.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.