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Diss Factsheets
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EC number: 201-210-7 | CAS number: 79-50-5
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 25-08-2009 / 21-10-2009
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: see 'Remark'
- Remarks:
- Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Report date:
- 2009
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling point/boiling range)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- differential scanning calorimetry
Test material
- Reference substance name:
- RS-Pantolactone
- IUPAC Name:
- RS-Pantolactone
- Reference substance name:
- (±)-dihydro-3-hydroxy-4,4-dimethylfuran-2(3H)-one
- EC Number:
- 201-210-7
- EC Name:
- (±)-dihydro-3-hydroxy-4,4-dimethylfuran-2(3H)-one
- Cas Number:
- 79-50-5
- Molecular formula:
- C6H10O3
- IUPAC Name:
- (±)-dihydro-3-hydroxy-4,4-dimethylfuran-2(3H)-one
- Details on test material:
- - Name of test material (as cited in study report): RS-Pantolactone
- Physical state: Waxy Solid, white
- Analytical purity: 99.7 %
- Lot/batch No.: Bx TL 00905003
- Expiration date of the lot/batch: May 2011
- Storage condition of test material: At room temperature at about 20 °C
Constituent 1
Constituent 2
Results and discussion
Boiling point
- Boiling pt.:
- 242.4 °C
- Atm. press.:
- 98.9 kPa
- Decomposition:
- no
Any other information on results incl. tables
The determinations of the boiling point/boiling range of the test item were performed according to Council Regulation (EC) No. 440/2008, A.2 Boiling temperature and to the OECD Guideline No. 103: Boiling Point, adopted July 27, 1995.
Preliminary Test
Several endothermic heat effects were observed, the first peak starting at 66.5 °C. After the experiment, the sample had lost about 100% of its mass. The cup was empty and there was no residue.
Main Test
To confirm the results obtained during the preliminary tests, a further DSC run was performed in the temperature range between 190 °C and 290 °C using a sample cube with a defined perforation.
During this first main test run, an endothermic reaction was observed at 242.1 °C. Therefore, another main test run was recorded within the immediate vicinity of the peak temperature (190 °C 290 °C) with a temperature rise of 10 °C/min. In the second DSC run the boiling was observed at 242.7 °C. After the experiment, the cup was completely empty and the test item lost about 99.0% to 99.8%, respectively, of its mass.
The atmospheric pressure during the measurements was 98.9 kPa (first and second main test).
The results of the individual measurements are summarized in the table below.
Applicant's summary and conclusion
- Conclusions:
- The boiling point of RS-Pantolactone was determined to be
242.4 °C,
which is equal to 515.6 K.
The estimated accuracy is ± 0.5 K. - Executive summary:
The boiling point of RS-Pantolactone was determined to be 242.4 °C which is equal to 515.6 K using thermal analysis (DSC).
The atmospheric pressure during the measurements was 98.9 kPa.
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