Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 434-630-6 | CAS number: 60372-77-2
Particle size distribution (Granulometry)
Administrative data
Link to relevant study record(s)
- Endpoint:
- particle size distribution (granulometry)
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2000-04-05
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- A guideline study with GLP.
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 110 (Particle Size Distribution / Fibre Length and Diameter Distributions)
- Deviations:
- no
- GLP compliance:
- yes
- Type of method:
- sieving
- Type of distribution:
- mass based distribution
- Specific details on test material used for the study:
- L.A.E.
Appearance: White solid
Batch: 2625
Expiry date: April 2001
Purity: 92-94% - No.:
- #1
- Size:
- > 400 µm
- Distribution:
- 59 %
- No.:
- #2
- Size:
- 125 - 400 µm
- Distribution:
- 33.1 %
- No.:
- #3
- Size:
- 75 - 125 µm
- Distribution:
- 5.5 %
- No.:
- #4
- Size:
- 30 - 75 µm
- Distribution:
- 2.3 %
- No.:
- #5
- Size:
- 10 - 30 µm
- Distribution:
- 0.1 %
- No.:
- #6
- Size:
- < 10 µm
- Distribution:
- 0 %
- Conclusions:
- The result indicates that 0% by mass of Nα-Lauroyl-L-arginine ethyl ester monohydrochloride (LAE) is smaller than 10 µm.
- Executive summary:
The determination of particle size distribution of Nα-Lauroyl-L-arginine ethyl ester monohydrochloride was realized using sieve analysis:
Particle size (µm)
% by weight
>400
59.0
400-125
33.1
125-75
5.5
75-30
2.3
30 -10
0.1
<10
0
The results indicates that 0% by mass of LAE is smaller than 10 µm.
Reference
As 2.3% of the test material was less than 75 µm in diameter, image analysis was not performed.
Description of key information
Key study: Test method OECD 110. GLP Study. The result indicates that 0% by mass of Nα-Lauroyl-L-arginine ethyl ester monohydrochloride (LAE) is smaller than 10 micrometers.
Additional information
Key study 1: The determination of particle size distribution of Nα-Lauroyl-L-arginine ethyl ester monohydrochloride (LAE) was realized using sieve analysis:
Particle size (µm) |
% by weight |
>400 |
59.0 |
400-125 |
33.1 |
125-75 |
5.5 |
75-30 |
2.3 |
30 -10 |
0.1 |
<10 |
0 |
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
