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EC number: 936-276-2 | CAS number: -
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Long-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
According to transformation/dissolution study (OECD guidance 29) conducted for the substance, the most critical constituents leachable to water from this UVCB substance are lead and zinc compounds. Therefore, the chemical safety assessment focuses on the properties of constituents and the key values for CSA are selected based on the read-across data on the most bioavailable compounds of Pb and Zn.
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 18.9 µg/L
Marine water fish
Marine water fish
- Effect concentration:
- 229.6 µg/L
Additional information
The environmental hazard assessment was conducted based on the most critical constituents of the substance. The critical constituents were selected based on the transformation/dissolution study (OECD guidance 29) was conducted for the substance target substance.
According to the chemical composition analysis, the main phases of the substance are lead sulphate and zinc sulphide. The product consists primarily of sulphur (ca. 35 %), lead (ca. 25 %) and zinc (ca. 17 %) together with minor trace elements such as silver, silicon, aluminium, calcium and iron.
According to T/D study results, the most soluble and critical components of this substance are lead and zinc. Therefore, the studies for this endpoint have been selected as a read-across data for the critical constituents. The read-across justification is presented in CSR annex I. All read-across data for ecotoxicology are based on test data using either soluble Pb or Zn salts or measured (dissolved) Pb or Zn concentrations. The weight of evidence approach was used to make conclusions on the key value for CSA.
Toxicity of lead and its compound
Freshwater:
The high quality chronic freshwater database contains toxicity data towards lead for 6 freshwater fish species (Oncorhynchus mykiss, Salvelinus fontinalis, Pimephales promelas, Lepomis macrochirus, Salvelinus namaycush, Ictalurus punctatus, Salmo salar). No-effect levels for dissolved lead for fish were situated between 18.9 µg Pb/L (Oncorhynchus mykiss; endpoint: scoliosis) and 1558.6 µg Pb/L (Pimephales promelas; endpoint: dry weight).
The lowest chronic toxicity (NOEC 570-d Oncorhynchus mykiss (abnormalitites: scoliosis)) value: 18.9 µg/l (CI 18.2-19.6 µg/L, no guideline)
Marine:
The chronic toxicity database for marine fish contains result for 1 marine fish with NOEC 28 -d result of 229.6 µg/l (Cyprinodon variegatus, endpoint: dry weight).
The lowest toxicity (NOEC 28-d, Cyprinodon variegatus (dry weight)) value: 229.6 µg/l (CI 155.1 - 339.9 µg/L, ASTM Method E1241 2003)
Toxicity of zinc and its compounds
Freshwater
Species NOECs have been put into the respective species sensitivity distributions. Extensive high quality chronic data were available on 7 (freshwater) and 1 (marine) fish species. These data were all screened for relevancy to the environment under study.
The freshwater species are part of 4 families: Cyprinodontidae (Jordanella), Cyprinidae (Phoxinus, Pimephales), Salmonidae (Oncorrhynchus, Salvelinus, Salmo trutta) and Cottidae (Cottus). Species NOECs range between 0.044 and 0.530 mg Zn/l (dissolved concentrations). The sensitivity of these species is equally distributed over the species sensitivity distribution. The fish species NOECs are combined with the other freshwater chronic data in the SSD to give the HC5 from which the PNEC is derived. Lowest single NOEC was 0.039 mg/L (NOEC 30-d Oncorhynchus mykiss).
The lowest toxicity (NOEC 30-d, Oncorhynchus mykiss (mortality)) value: 0.039 mg/l (OECD 215)
Marine
The saltwater species comes from the family Clupeidae (Clupea harengus). This species is not among the most sensitive ones in the species sensitivity distribution. The fish species NOEC is combined with the other marine chronic data in the SSD to give the HC5 from which the PNEC saltwater is derived. NOEC = 0.025 mg Zn/l (NOEC 27-d Clupea harengus) (dissolved concentrations)
The lowest toxicity (NOEC 27-d, Clupea harengus (development)) value: 0.025 mg (no guideline)
Conclusions for CSA:
Toxicity of the test substance is evaluated by using WoE read-across data from the two critical components of the test substance (zinc and lead). From the toxicity data, lead has the lowest key values for long-term toxicity to fresh water fish. Therefore, the toxicity values from lead were used as key values for CSA. However, as lead and zinc are both relevant for environmental ES&RC, key values from both constituents were taken into account in the exposure assessment (see section 9&10 of CSR). All relevant fish chronic values for lead and zinc were used as a part of the PNEC derivation (statistical extrapolation method).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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