Registration Dossier
Registration Dossier
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A mixture of isomers of: 1,1'-[(3,5(or 2,4 or 4,6 or 2,6)-dihydroxy-o(or m or p)-phenylene)bis(azo-meta-phenyleneazo{1-[3-(dimethylamino)propyl]-1,2-dihydro-6-hydroxy-4-methyl-2-oxopyridine-5,3-diyl})]dipyridinium-dichloride-dihydrochloride; 1-(1-[3-(dimethylamino)propyl]-5-{3-[x-(4-{1-[3-(dimethylamino)propyl]-1,6-dihydro-2-hydroxy-4-methyl-6-oxo-5-pyridinio-3-pyridylazo}phenylazo)-2,4(or 2,6 or 3,5 or 4,6)-dihydroxyphenylazo]phenylazo}-1,2-dihydro-6-hydroxy-4-methyl-2-oxo-3-pyridyl)pyridinium-dichloride-dihydrochloride (where x is variable)
EC number: 404-540-1 | CAS number: 159405-95-5 BRAUN HM 2763; BROWN HM 2763; BRUN HM 2763; BRUNO HM 2763
Endpoint summary
Administrative data
Description of key information
Stability
Study on hydrolysis proposed to get waived, based on knowledge from handling and use of the substance indicating hydrolytical stability in the relevant pH range 3.5 - 9.5.
Biodegradation
The substance showed neither ready nor inherent biodegradability. Biodegradation simulation studies in water and sediment as well as biodegradability in soil can get waived. Based on the available data the substance shall be considered as not biodegradable.
Bioaccumulation
Study on bioaccumulation proposed to get waived based on log Kow < 0. The substance therefore shall be considered as not bioaccumulative.
Transport and distribution
Study on transport and distribution proposed to get waived based on log Kow < 0. The substance is expected to have very low potential for adsorbance to particulate matter and therefore shall be considered as highly mobile in the different environmental compartments.
Additional information
Test substance is considered as chemically stable. As the the substance also was not readily or inherently biodegradable, according to ECHA guidance documents the substance shall be assessed as persistent for the time being, unless further data would indicate differently.
The studies on bioaccumulation and adsorption/desorption both are proposed to get waived based on the low log Kow < 0 and high solubility in water. The substance thus shall be considered as not being bioaccumulative, and as being highly mobile in soil and sediments.
Based on these grounds the PBT and vPvB discussion stops at this point.
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