Registration Dossier
Registration Dossier
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EC number: 434-850-2 | CAS number: 1680-31-5
Hydrolysis
Administrative data
Link to relevant study record(s)
Description of key information
According to the results the test item is considered to be hydrolytically not stable in the presence of an intestinal-fluid simulant. In presence of saliva simulant or gastric-juice simulant it could be shown that the test item hydrolyses slightly.
Key value for chemical safety assessment
Additional information
The hydrolysis of the test item in the presence of several fluids (saliva simulant, gastric-juice simulant and intestinal-fluid simulant) was investigated using gas chromatography. After termination of the hydrolysis test at 37 °C the hydrolysis product (octanol) was determined in the hydrolysate.
The recovery of octanol in saliva simulant, in gastric juice and in intestinal-fluid simulant were 2 %, 7 % and 60 %, respectively. Thus according to the results the test item is considered to be hydrolytically not stable in the presence of an intestinal-fluid simulant. In presence of saliva simulant or gastric-juice simulant the test item is considered to hydrolyses slightly.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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