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Toxicological information

Carcinogenicity

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Description of key information

There is no study available to examine the carcinogenic potential of trimethylolpropane as the substance is not suspected to be carcinogenic. Trimethylolpropane has been demonstrated to be not genotoxic and no (histo)pathological alterations indicative for a potential carcinogenic effect were observed in the available repeat dose toxicity studies.

Key value for chemical safety assessment

Carcinogenicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no study available

Carcinogenicity: via dermal route

Endpoint conclusion
Endpoint conclusion:
no study available

Additional information

There is no study available to examine the carcinogenic potential of trimethylolpropane.

According to ANNEX X of Regulation (EC) No. 1907/2006 there is no need to propose or to require a carcinogenicity study because the substance proved to be not mutagenic and no (histo)pathological alterations indicative for a potential carcinogenic effect were observed in the available repeat dose toxicity studies.

Justification for classification or non-classification

There is no study available to examine the carcinogenic potential of trimethylolpropane. Trimethylolpropane has been demonstrated not to be genotoxic and no (histo)pathological alterations indicative for a potential carcinogenic effect were observed in the available repeat dose toxicity studies.