Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
eye irritation: in vivo
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: No data on materials and methods; the authors reference to a publication which is written in Russian language.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1988

Materials and methods

Principles of method if other than guideline:
Method is described in: "Problems of industrial toxicology, Editorial section of the managing department of the Secretariat of CMEA." Title: "Methodological instructions for the organization of studies for the substantiation of standards of harmful substances in the air of the working zone" (in Russian)
GLP compliance:
not specified

Test material

Constituent 1
Reference substance name:
12539-71-8
Cas Number:
12539-71-8
IUPAC Name:
12539-71-8
Details on test material:
- Name of test material (as cited in study report): zinc carbonate basic monohydrate (2ZnCO3 . 3Zn(OH)2 . H2O)

Test animals / tissue source

Species:
rabbit
Strain:
not specified
Details on test animals or tissues and environmental conditions:
no data

Test system

Vehicle:
not specified
Controls:
not specified
Amount / concentration applied:
no data
Duration of treatment / exposure:
no data
Observation period (in vivo):
no data
Number of animals or in vitro replicates:
no data

Results and discussion

In vivo

Results
Irritation parameter:
overall irritation score
Remarks:
Irritation
Basis:
other: all animals
Time point:
other: no data
Score:
ca. 0
Reversibility:
other: not applicable
Remarks on result:
other: The results of the study (irritation effects) are only described (without the presentation of numbers). It is stated that the test substance does not show an irritative effect on the mucous membranes of the eyes.

Applicant's summary and conclusion