Registration Dossier
Registration Dossier
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EC number: 226-076-7 | CAS number: 5263-02-5
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: No data on materials and methods; the authors reference to a publication which is written in Russian language.
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 988
Materials and methods
- Principles of method if other than guideline:
- Method is described in: "Problems of industrial toxicology, Editorial section of the managing department of the Secretariat of CMEA." Title: "Methodological instructions for the organization of studies for the substantiation of standards of harmful substances in the air of the working zone" (in Russian)
- GLP compliance:
- not specified
Test material
- Reference substance name:
- 12539-71-8
- Cas Number:
- 12539-71-8
- IUPAC Name:
- 12539-71-8
- Details on test material:
- Name of test material (as cited in study report): zinc carbonate basic monohydrate (2 ZnCO3 . 3Zn(OH)2 . H2O))
Constituent 1
Test animals
- Species:
- other: rabbit, guinea pig, rat
- Strain:
- not specified
Test system
- Type of coverage:
- not specified
- Preparation of test site:
- not specified
- Vehicle:
- not specified
- Controls:
- not specified
- Amount / concentration applied:
- no data
- Duration of treatment / exposure:
- no data
- Observation period:
- the reaction of the skin is recorded 1 and 16 h after a single application
- Number of animals:
- no data
Results and discussion
In vivo
Results
- Irritation parameter:
- overall irritation score
- Basis:
- other: all animals tested
- Time point:
- other: 1 h an 16 h
- Score:
- ca. 0
- Reversibility:
- other: not applicable
- Remarks on result:
- other: The results of the study (irritation effects) are only described (without the presentation of numbers). It is stated that the test substance does not show an irritative effect on the skin.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
